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Article

Identifying chromosomal subpopulations based on their recombination histories advances the study of the genetic basis of phenotypic traits.

Genome research - 1 Dec 2020

Ruiz-Arenas Carlos, Cáceres Alejandro, López Marcos, Pelegrí-Sisó Dolors, González Josefa, González Juan R

Abstract excerpt

Recombination is a main source of genetic variability. However, the potential role of the variation generated by recombination in phenotypic traits, including diseases, remains unexplored because there is currently no method to infer chromosomal subpopulations based on recombination pattern differences. We developed recombClust, a method that uses SNP-phased data to detect differences in historic recombination in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33203765
DOI: 10.1101/gr.258301.119
PMCID: PMC7706724

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