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Article

Influence of Mitochondrial Genetics on the Mitochondrial Toxicity of Linezolid in Blood Cells and Skin Nerve Fibers.

Antimicrobial agents and chemotherapy - 1 Sept 2017

Garrabou G, Soriano À, Pinós T, Casanova-Mollà J, Pacheu-Grau D, Morén C, García-Arumí E, Morales M, Ruiz-Pesini E, Catalán-Garcia M, Milisenda J C, Lozano E, Andreu A L, Montoya J, Mensa J, Cardellach F

Abstract excerpt

The antibiotic linezolid is a ribosomal inhibitor with excellent efficacy. Although the administration period has been reduced to 28 days, side effects, usually of hematologic or neuropathic origin, are still reported due to secondary inhibition of mitochondrial protein synthesis. Susceptibility to linezolid toxicity remains unknown. Therefore, the objective of this study was to gain an understanding of clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28674062
DOI: 10.1128/AAC.00542-17
PMCID: PMC5571298

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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