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Article

High altitude and pre-eclampsia: Adaptation or protection.

Medical hypotheses - 1 Jul 2017

Ahmed Sarah I Y, Ibrahim Muntaser E, Khalil Eltahir A G

Abstract excerpt

Adaptive genes of high altitude can also be protective in diseases like preeclampsia, hypertension, and diabetes mellitus, Alzheimer, Parkinson Disease and Cancer, which may result from deregulation of hypoxia pathway. The example of pre-eclampsia and normal pregnancy were studied to see if the hypoxia-induced disorders can be dragged towards adaptation. Here, we analyse the genetic variants that are known to be...

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Share to Altitude
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypoxia

Share to Hypoxia-Inducible Factor-Proline Dioxygenases

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Share to Pregnancy Complications

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Source

Identifiers

PMID: 28673571
DOI: 10.1016/j.mehy.2017.05.007

Genes

ADAM9
EGLN1
EPAS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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