Article
1700012B09Rik, a FOXJ1 effector gene active in ciliated tissues of the mouse but not essential for motile ciliogenesis.
Developmental biology - 1 Sept 2017
Stauber Michael, Boldt Karsten, Wrede Christoph, Weidemann Marina, Kellner Manuela, Schuster-Gossler Karin, Kühnel Mark Philipp, Hegermann Jan, Ueffing Marius, Gossler Achim
Abstract excerpt
In humans and mice, motile cilia occur on the surface of the embryonic ventral node, on respiratory and ependymal epithelia and in reproductive organs where they ensure normal left-right asymmetry of the organism, mucociliary clearance of airways, homeostasis of the cerebrospinal fluid and fertility. The genetic programme for the formation of motile cilia, thus critical for normal development and health, is...
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