Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allopregnanolone levels and depressive symptoms during pregnancy in relation to single nucleotide polymorphisms in the allopregnanolone synthesis pathway.

Hormones and behavior - 1 Aug 2017

Hellgren Charlotte, Comasco Erika, Skalkidou Alkistis, Sundström-Poromaa Inger

Abstract excerpt

Allopregnanolone, a neurosteroid whose levels rise throughout gestation, putatively stabilizes antenatal mood. The present study aimed to investigate associations of plasma allopregnanolone to antenatal depressive symptoms, as well as to genetic and obstetric factors. Allopregnanolone plasma levels from 284 pregnant women were measured around gestational week 18. Haplotype tag single nucleotide polymorphisms in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3-Oxo-5-alpha-Steroid 4-Dehydrogenase
Share to Depression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depression, Postpartum

Share to Hydroxysteroid Dehydrogenases

Share to Metabolic Networks and Pathways

Share to Oxidoreductases

Share to Pregnancy Complications

Share to Psychiatric Status Rating Scales

Source

Identifiers

PMID: 28666923
DOI: 10.1016/j.yhbeh.2017.06.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allopregnanolone levels and depressive symptoms during pregnancy in relation to single nucleotide polymorphisms in the allopregnanolone synthesis pathway.PMID 28666923Read ↗

An update on the physiologic changes during pregnancy and their impact on drug pharmacokinetics and pharmacogenomicsSemantic proximity Read ↗

Regulation of mRNA expression encoding chaperone and co-chaperone proteins of the glucocorticoid receptor in peripheral blood: association with depressive symptoms during pregnancySemantic proximity Read ↗

Associations between Medication Use and Restless Legs Syndrome in Pregnancy among Nulliparous Individuals: A Secondary Analysis of the nuMoM2b Study.Semantic proximity Read ↗

Genetic variants in the genes of the sex steroid hormone metabolism and depressive symptoms during and after pregnancy.Semantic proximity Read ↗

Changes in human placental 5a-reductase isoenzyme expression with advancing gestation: effects of fetal sex and glucocorticoid exposureSemantic proximity Read ↗

Gender-specific association of variants in the AKR1C1 gene with dimensional anxiety in patients with panic disorder: additional evidence for the importance of neurosteroids in anxiety?Semantic proximity Read ↗

Maternal Age at Menarche Genes Determines Fetal Growth Restriction Risk.Semantic proximity Read ↗

Polymorphisms in AKR1C4 and HSD3B2 and differences in serum DHEAS and progesterone are associated with paranoid ideation during mania or hypomania in bipolar disorder.Semantic proximity Read ↗

A functional fetal HSD11B2[CA]n microsatellite polymorphism is associated with maternal serum cortisol concentrations in pregnant women.Semantic proximity Read ↗

Maternal depression and anxiety are associated with altered gene expression in the human placenta without modification by antidepressant use: Implications for fetal programmingSemantic proximity Read ↗

Cytokines and tryptophan metabolites can predict depressive symptoms in pregnancySemantic proximity Read ↗

Association study of 44 candidate genes with depressive and anxiety symptoms in post-partum women.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.