Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Changes in human placental 5a-reductase isoenzyme expression with advancing gestation: effects of fetal sex and glucocorticoid exposure

16 Apr 2009

Abstract excerpt

5alpha-reduced steroids, including allopregnanolone, suppress neuronal activity and can have neuroprotective effects in the fetus. 5alpha-reductases in the placenta may contribute precursors to brain allopregnanolone synthesis. Preterm birth and glucocorticoids, administered for fetal lung maturation or for maternal asthma, may influence reductase expression. The aims of the present study were to evaluate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Gestational Diabetes Research and Management
Share to Pregnancy and preeclampsia studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19383266
DOI: 10.1071/rd08224

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Changes in human placental 5a-reductase isoenzyme expression with advancing gestation: effects of fetal sex and glucocorticoid exposurePMID 19383266Read ↗

Expression of eight glucocorticoid receptor isoforms in the human preterm placenta vary with fetal sex and birthweightSemantic proximity Read ↗

The human placenta expresses multiple glucocorticoid receptor isoforms that are altered by fetal sex, growth restriction and maternal asthmaSemantic proximity Read ↗

Dual Function of 11β-Hydroxysteroid Dehydrogenase in Placenta: Modulating Placental Glucocorticoid Passage and Local Steroid Action1Semantic proximity Read ↗

Prenatal exposure to dexamethasone in the mouse induces sex‐specific differences in placental gene expressionSemantic proximity Read ↗

11β-HSD1 in Human Fetal Membranes as a Potential Therapeutic Target for Preterm BirthSemantic proximity Read ↗

Alterations in Human Placental 11β-hydroxysteroid Dehydrogenase Type 1 and 2 with Gestational Age and LabourSemantic proximity Read ↗

Landscape of Steroid Dynamics in Pregnancy: Insights From the Maternal-Placental-Fetal Unit and Placental ModelsSemantic proximity Read ↗

Deciphering the Dichotomy: The Role of Glucocorticoid Receptor Isoforms in Cortisol’s Paradoxical Impact on Reproduction and PregnancySemantic proximity Read ↗

Expression of glucocorticoid receptor messenger ribonucleic acid transcripts in the human placenta at term.Semantic proximity Read ↗

Allopregnanolone levels and depressive symptoms during pregnancy in relation to single nucleotide polymorphisms in the allopregnanolone synthesis pathway.Semantic proximity Read ↗

Foetal and placental 11<i>β</i>‐<scp>HSD</scp>2: a hub for developmental programmingSemantic proximity Read ↗

Antenatal Glucocorticoid Exposure Results in Sex-Specific and Transgenerational Changes in Prefrontal Cortex Gene Transcription that Relate to Behavioural OutcomesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.