Article
A functional fetal HSD11B2[CA]n microsatellite polymorphism is associated with maternal serum cortisol concentrations in pregnant women.
Kidney & blood pressure research - 1 Jan 2013
Li Jian, Chen You-Peng, Wang Zi-Neng, Liu Tie-Bin, Chen Dan, Dong Yun-Peng, Hocher Berthold
Abstract excerpt
BACKGROUND/AIMS: Cortisol plays an important role during pregnancy. It controls maternal glucose metabolism and fetal development. Cortisol metabolism is partially controlled by the 11b-HSD2. This enzyme is expressed in the kidney and human placenta. The activity of the enzyme is partially controlled by functional polymorphisms: the HSD11B2[CA]n microsatellite polymorphism. The impact of this functional gene...
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