An update on the physiologic changes during pregnancy and their impact on drug pharmacokinetics and pharmacogenomics

Abstract excerpt

For many years, the medical community has relied in clinical practice on historic data about the physiological changes that occur during pregnancy. However, some newer studies have disputed a number of assumptions in these data for not being evidence-based or derived from large prospective cohort-studies. Accurate knowledge of these physiological changes is important for three reasons: Firstly, it facilitates...

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