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Article

No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice.

Scientific reports - 29 Jun 2017

Rolseth Veslemøy, Luna Luisa, Olsen Ann Karin, Suganthan Rajikala, Scheffler Katja, Neurauter Christine G, Esbensen Ying, Kuśnierczyk Anna, Hildrestrand Gunn A, Graupner Anne, Andersen Jill M, Slupphaug Geir, Klungland Arne, Nilsen Hilde, Bjørås Magnar

Abstract excerpt

Base excision repair (BER) is a major pathway for removal of DNA base lesions and maintenance of genomic stability, which is essential in cancer prevention. DNA glycosylases recognize and remove specific lesions in the first step of BER. The existence of a number of these enzymes with overlapping substrate specificities has been thought to be the reason why single knock-out models of individual DNA glycosylases...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28663564
DOI: 10.1038/s41598-017-04472-4
PMCID: PMC5491499

Genes

NEIL1
NEIL2
NEIL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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