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Article

Genetic determinants of facial clefting: analysis of 357 candidate genes using two national cleft studies from Scandinavia.

PloS one - 1 Jan 2009

Jugessur Astanand, Shi Min, Gjessing Håkon Kristian, Lie Rolv Terje, Wilcox Allen James, Weinberg Clarice Ring, Christensen Kaare, Boyles Abee Lowman, Daack-Hirsch Sandra, Trung Truc Nguyen, Bille Camilla, Lidral Andrew Carl, Murray Jeffrey Clark

Abstract excerpt

BACKGROUND: Facial clefts are common birth defects with a strong genetic component. To identify fetal genetic risk factors for clefting, 1536 SNPs in 357 candidate genes were genotyped in two population-based samples from Scandinavia (Norway: 562 case-parent and 592 control-parent triads; Denmark...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 19401770
DOI: 10.1371/journal.pone.0005385
PMCID: PMC2671138

Genes

PDGFC
ALX3
ETV5
FGF12
MKX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19401770-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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