Article
A Role of the ABCC4 Gene Polymorphism in Airway Inflammation of Asthmatics.
Mediators of inflammation - 1 Jan 2017
Palikhe Sailesh, Uuganbayar Udval, Trinh Hoang Kim Tu, Ban Ga-Young, Yang Eun-Mi, Park Hae-Sim, Kim Seung-Hyun
Abstract excerpt
The ATP-binding cassette subfamily C member 4 gene encodes a transmembrane protein involved in the export of proinflammatory molecules, including leukotriene, prostaglandin, and sphingosine-1-phosphate across the plasma membrane. Those metabolites play important roles in asthma. We investigated the potential associations between ABCC4 gene polymorphisms and asthma phenotype. In total, 270 asthma patients and 120...
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