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Article

Caveolae Protect Notochord Cells against Catastrophic Mechanical Failure during Development.

Current biology : CB - 10 Jul 2017

Lim Ye-Wheen, Lo Harriet P, Ferguson Charles, Martel Nick, Giacomotto Jean, Gomez Guillermo A, Yap Alpha S, Hall Thomas E, Parton Robert G

Abstract excerpt

The embryonic notochord is a flexible structure present during development that serves as scaffold for formation of the vertebrate spine. This rod-like organ is thought to have evolved in non-vertebrate chordates to facilitate locomotion by providing a rigid but flexible midline structure against which the axial muscles can contract. This hydrostatic "skeleton" is exposed to a variety of mechanical forces during...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28648821
DOI: 10.1016/j.cub.2017.05.067

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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