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From embryonic development to human diseases: The functional role of caveolae/caveolin

1 Mar 2016

Abstract excerpt

Caveolae, an almost ubiquitous, structural component of the plasma membrane, play a critical role in many functions essential for proper cell function, including membrane trafficking, signal transduction, extracellular matrix remodeling, and tissue regeneration. Three main types of caveolin proteins have been identified from caveolae since the discovery of caveolin-1 in the early 1990s. All three (Cav-1, Cav-2,...

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PMID: 26991990
DOI: 10.1002/bdrc.21121

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