Article
Transposable Elements Mediate Adaptive Debilitation of Flagella in Experimental Escherichia coli Populations.
Journal of molecular evolution - 1 Jun 2017
Plague Gordon R, Boodram Krystal S, Dougherty Kevin M, Bregg Sandar, Gilbert Daniel P, Bakshi Hira, Costa Daniel
Abstract excerpt
Although insertion sequence (IS) elements are generally considered genomic parasites, they can mediate adaptive genetic changes in bacterial genomes. We discovered that among 12 laboratory-evolved Escherichia coli populations, three had experienced at least six different IS1-mediated deletions of flagellar genes. These deletions all involved the master flagellar regulator flhDC, and as such completely...
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