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Article

BORIS up-regulates OCT4 via histone methylation to promote cancer stem cell-like properties in human liver cancer cells.

Cancer letters - 10 Sept 2017

Liu Qiuying, Chen Kefei, Liu Zhongjian, Huang Yuan, Zhao Rongce, Wei Ling, Yu Xiaoqin, He Jingyang, Liu Jun, Qi Jianguo, Qin Yang, Li Bo

Abstract excerpt

Accumulating evidence has revealed the importance of cancer stem cells (CSCs) in chemoresistance and recurrence. BORIS, a testes-specific CTCF paralog, has been shown to be associated with stemness traits of embryonic cancer cells and epithelial CSCs. We previously reported that BORIS is correlated with the expression of the CSC marker CD90 in hepatocellular carcinoma (HCC). These results encourage us to wonder...

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Source

Identifiers

PMID: 28645561
DOI: 10.1016/j.canlet.2017.06.017

Genes

CTCF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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