Article
Adiponectin Isoform Patterns in Ethnic-Specific ADIPOQ Mutation Carriers: The IRAS Family Study.
Obesity (Silver Spring, Md.) - 1 Aug 2017
Tabb Keri L, Gao Chuan, Hicks Pamela J, Hawkins Gregory A, Rotter Jerome I, Chen Yii-Der Ida, Guo Xiuqing, Norris Jill M, Lorenzo Carlos, Freedman Barry I, Bowden Donald W, Palmer Nicholette D
Abstract excerpt
OBJECTIVE: Adiponectin is found in human serum in three groups of multimers (high molecular weight [HMW], medium molecular weight [MMW], and low molecular weight [LMW]). Two ethnic-specific variants in ADIPOQ, G45R (Hispanic-Americans) and R55C (African-Americans), were previously reported. Although carriers of both variants had mean adiponectin levels ≤ 20% of those of noncarriers, they were not clinically...
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