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Article

Population-specific coding variant underlies genome-wide association with adiponectin level

18 Oct 2011

Abstract excerpt

Adiponectin is a protein hormone that can affect major metabolic processes including glucose regulation and fat metabolism. Our previous genome-wide association (GWA) study of circulating plasma adiponectin levels in Filipino women from the Cebu Longitudinal Health and Nutrition Survey (CLHNS) detected a 100 kb two-SNP haplotype at KNG1-ADIPOQ associated with reduced adiponectin (frequency = 0.050, P = 1.8 ×...

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PMID: 22010046
DOI: 10.1093/hmg/ddr480

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