Article
Genome-wide linkage of plasma adiponectin reveals a major locus on chromosome 3q distinct from the adiponectin structural gene: the IRAS family study.
Diabetes - 1 Jun 2006
Guo Xiuqing, Saad Mohammed F, Langefeld Carl D, Williams Adrienne H, Cui Jinrui, Taylor Kent D, Norris Jill M, Jinagouda Sujata, Darwin Christine H, Mitchell Braxton D, Bergman Richard N, Sutton Beth, Chen Y-D Ida, Wagenknecht Lynne E, Bowden Donald W, Rotter Jerome I
Abstract excerpt
Adiponectin (APM1) is an adipocyte-derived peptide that contributes to glucose, lipid, and energy homeostasis. We assessed the genetic basis of plasma adiponectin in Hispanic-American and African-American families enrolled through the Insulin Resistance Atherosclerosis Study Family Study. A 10-cM genome scan was performed in two batches: an original set (set 1) consisting of 66 families (45 Hispanic American and...
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