Article
Genetic variants in cell death pathway genes and HBV-related hepatocellular carcinoma among a Chinese Han population.
Apoptosis : an international journal on programmed cell death - 1 Aug 2017
Liu Fei, Li Fuqiang, Luo Limei, Yang Hanteng, Wei Yonggang, Wang Wentao, Yan Lvnan, Wen Tianfu, Yang Jiayin, Li Bo
Abstract excerpt
Cell death pathway plays an important role in apoptosis, and corruption of this signaling pathway has been shown to participate in carcinogenesis. We aimed at determining whether genetic variants in CASP8, CASP10 and CFLAR influence the development and clinical outcomes of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). A hospital-based case-control study, including 600 HCC cases and 600 HBsAg...
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