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Article

Association between immunoglobulin heavy-chain variable region mutational status and isolated favorable baseline genomic aberrations in chronic lymphocytic leukemia.

Leukemia & lymphoma - 1 Jan 2018

Sandoval-Sus Jose D, Chavez Julio C, Dalia Samir, Naqvi Syeda Mahrukh Hussnain, Talati Chetasi, Nodzon Lisa, Kharfan-Dabaja Mohamed A, Pinilla-Ibarz Javier

Abstract excerpt

Immunoglobulin heavy-chain variable region (IGHV) mutational status and karyotype abnormalities are important prognostic factors in chronic lymphocytic leukemia (CLL). The goal was to assess the impact of IGHV in CLL patients with isolated favorable genetic aberrations (del13q, trisomy 12, or negative fluorescence in situ hybridization [FISH]). We studied 273 CLL patients with both IGHV mutational status and...

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Share to Chromosomes, Human, Pair 12
Share to Immunoglobulin Heavy Chains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin Variable Region

Share to In Situ Hybridization, Fluorescence

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Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Source

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Identifiers

PMID: 28641468
DOI: 10.1080/10428194.2017.1323271
PMCID: PMC7771359

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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