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Article

Microtubule-dependent oligomerization of tau. Implications for physiological tau function and tauopathies.

The Journal of biological chemistry - 29 Aug 2003

Makrides Victoria, Shen Ting E, Bhatia Rajinder, Smith Bettye L, Thimm Julian, Lal Ratneshwar, Feinstein Stuart C

Abstract excerpt

The accumulation of abnormal tau filaments is a pathological hallmark of many neurodegenerative diseases. In 1998, genetic analyses revealed a direct linkage between structural and regulatory mutations in the tau gene and the neurodegenerative disease, frontotemporal dementia with parkinsonism li...

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Identifiers

PMID: 12805366
DOI: 10.1074/jbc.M305207200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12805366-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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