Article

Leishmania guyanensis controls endogenous viral replication by a canonical RNA interference pathway

2026-08-10

Abstract excerpt

Protistan parasites of the genus Leishmania, infamous human and animal pathogens, can themselves be infected by endosymbiotic viruses, exemplified by Leishmania RNA viruses (LRVs). These viruses affect immune responses in vertebrate hosts and have been associated with adverse treatment outcomes. How parasites control replication of these viruses is not known. Intriguingly, functional RNA interference (RNAi) pathwa...

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Literature Corpus work: ef979f6f-9264-5c5b-baac-ab4c2b076c71
DOI: 10.64898/2026.08.09.743808

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