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Article

Limited MHC class I intron 2 repertoire variation in bonobos.

Immunogenetics - 1 Oct 2017

de Groot Natasja G, Heijmans Corrine M C, Helsen Philippe, Otting Nel, Pereboom Zjef, Stevens Jeroen M G, Bontrop Ronald E

Abstract excerpt

Common chimpanzees (Pan troglodytes) experienced a selective sweep, probably caused by a SIV-like virus, which targeted their MHC class I repertoire. Based on MHC class I intron 2 data analyses, this selective sweep took place about 2-3 million years ago. As a consequence, common chimpanzees have a skewed MHC class I repertoire that is enriched for allotypes that are able to recognise conserved regions of the SIV...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28623393
DOI: 10.1007/s00251-017-1010-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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