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Cancer biology in ulcerative colitis and potential use in endoscopic surveillance.

Gastrointestinal endoscopy clinics of North America - 1 Jul 1997

Shapiro B D, Lashner B A

Abstract excerpt

Because patients with longstanding ulcerative colitis are at an increased risk for developing colorectal cancer, surveillance colonoscopy and colectomy for dysplasia or asymptomatic cancer is advised as a method of reducing cancer-related mortality. Generally, the use of dysplasia as a criterion for a positive test in cancer surveillance has performed poorly. The emerging field of colon cancer genetics has...

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PMID: 9177146

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