Article
Variable DNA methylation of aging-related genes is associated with male COPD.
Respiratory research - 4 Nov 2019
Du Xizi, Yuan Lin, Wu Mengping, Men Meichao, He Ruoxi, Wang Leyuan, Wu Shuangyan, Xiang Yang, Qu Xiangping, Liu Huijun, Qin Xiaoqun, Hu Chengping, Qin Ling, Liu Chi
Abstract excerpt
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a chronic lung inflammatory disease which has a close relationship with aging. Genome-wide analysis reveals that DNA methylation markers vary obviously with age. DNA methylation variations in peripheral blood have the potential to be biomarkers for COPD. However, the specific DNA methylation of aging-related genes in the peripheral blood of COPD patients...
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