Article
A genome-wide association study of quantitative computed tomographic emphysema in Korean populations.
Scientific reports - 17 Aug 2021
Sin Sooim, Choi Hye-Mi, Lim Jiwon, Kim Jeeyoung, Bak So Hyeon, Choi Sun Shim, Park Jinkyeong, Lee Jin Hwa, Oh Yeon-Mok, Lee Mi Kyeong, Hobbs Brian D, Cho Michael H, Silverman Edwin K, Kim Woo Jin
Abstract excerpt
Emphysema is an important feature of chronic obstructive pulmonary disease (COPD). Genetic factors likely affect emphysema pathogenesis, but this question has predominantly been studied in those of European ancestry. In this study, we sought to determine genetic components of emphysema severity and characterize the potential function of the associated loci in Korean population. We performed a genome-wide...
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