Article

Phenotypic diversity is caused by non-linear genetic interactions between two SNAREopathy genes

2025-05-07

Abstract excerpt

<title>Abstract</title> <p> Brain disorders caused by large effect mutations in single genes often present unexplained large phenotypic diversity, even among carriers of the same mutation. Here we examined genetic interactions as a possible explanation for this diversity for SNAREopathies, a group of neurodevelopmental disorders caused by <italic>de novo</italic> genetic variation in genes that together drive...

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Literature Corpus work: 62a12bab-b053-52c6-a8bd-a40490cafca6
DOI: 10.21203/rs.3.rs-6440830/v1

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