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Article

Network-based analysis predicts interacting genetic modifiers from a meta-mapping study of spike-wave discharge in mice.

Genes, brain, and behavior - 1 Apr 2024

Lara Montana Kay, Brabec Jeffrey L, Hernan Amanda E, Scott Rod C, Tyler Anna L, Mahoney J Matthew

Abstract excerpt

Absence seizures are characterized by brief lapses in awareness accompanied by a hallmark spike-and-wave discharge (SWD) electroencephalographic pattern and are common to genetic generalized epilepsies (GGEs). While numerous genes have been associated with increased risk, including some Mendelian forms with a single causal allele, most cases of GGE are idiopathic and there are many unknown genetic modifiers of...

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Identifiers

PMID: 38444174
DOI: 10.1111/gbb.12879
PMCID: PMC10915378

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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