Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of Padi2 as a novel angiogenesis-regulating gene by genome association studies in mice.

PLoS genetics - 1 Jun 2017

Khajavi Mehrdad, Zhou Yi, Birsner Amy E, Bazinet Lauren, Rosa Di Sant Amanda, Schiffer Alex J, Rogers Michael S, Krishnaji Subrahmanian Tarakkad, Hu Bella, Nguyen Vy, Zon Leonard, D'Amato Robert J

Abstract excerpt

Recent findings indicate that growth factor-driven angiogenesis is markedly influenced by genetic variation. This variation in angiogenic responsiveness may alter the susceptibility to a number of angiogenesis-dependent diseases. Here, we utilized the genetic diversity available in common inbred mouse strains to identify the loci and candidate genes responsible for differences in angiogenic response. The corneal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endothelial Cells
Share to Fibroblast Growth Factor 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Hydrolases

Share to Mice, Inbred Strains

Share to Neovascularization, Pathologic

Share to Protein-Arginine Deiminases

Share to Zebrafish

Source

Open in PubMed Open full text

Identifiers

PMID: 28617813
DOI: 10.1371/journal.pgen.1006848
PMCID: PMC5491319

Genes

PADI2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of Padi2 as a novel angiogenesis-regulating gene by genome association studies in mice.PMID 28617813Read ↗

Genetic loci that control vascular endothelial growth factor-induced angiogenesis.Semantic proximity Read ↗

Genetic loci that control the angiogenic response to basic fibroblast growth factor.Semantic proximity Read ↗

Genetic heterogeneity of skin microvasculature.Semantic proximity Read ↗

The classical pink-eyed dilution mutation affects angiogenic responsiveness.Semantic proximity Read ↗

The effect of genetic diversity on angiogenesis.Semantic proximity Read ↗

Genetic loci that control the size of laser-induced choroidal neovascularization.Semantic proximity Read ↗

Genome-wide expression analysis of wounded skin reveals novel genes involved in angiogenesis.Semantic proximity Read ↗

Epistatic interactions between modifier genes confer strain-specific redundancy for Tgfb1 in developmental angiogenesis.Semantic proximity Read ↗

PAD2 Overexpression in Transgenic Mice Promotes Spontaneous Skin NeoplasiaSemantic proximity Read ↗

Comparative analysis of the mouse and human peptidylarginine deiminase gene clusters reveals highly conserved non-coding segments and a new human gene, PADI6Semantic proximity Read ↗

Genetic heterogeneity of angiogenesis in miceSemantic proximity Read ↗

Role of Id proteins in embryonic and tumor angiogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.