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Application of droplet digital PCR combined with TaqMan real-time PCR in Dombrock blood group genotyping in Northwest China.

Vox sanguinis - 1 Jun 2023

Li Zhuolin, Wang Yufeng, Sun Mao, Chen Tangdong, Wu Yuanming, Chen Kun

Abstract excerpt

BACKGROUND AND OBJECTIVES: The Dombrock blood group system is based on the DO gene. DO*A and DO*B antigens are the result of a single-nucleotide polymorphism (SNP) on this gene. The introduction of Do antigens through blood transfusion or other invasive factors like infection may result in the production of Do antibodies, which may cause serious haemolytic transfusion reactions. In this study, TaqMan real-time...

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PMID: 37016275
DOI: 10.1111/vox.13428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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