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Article

Nkx2.5 is essential to establish normal heart rate variability in the zebrafish embryo

14 Jun 2017

Abstract excerpt

Heart rate variability (HRV) has become an important clinical marker of cardiovascular health and a research measure for the study of the cardiac conduction system and its autonomic controls. While the zebrafish ( Danio rerio) is an ideal vertebrate model for understanding heart development, HRV has only recently been investigated in this system. We have previously demonstrated that nkx2.5 and nkx2.7, two...

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PMID: 28615160
DOI: 10.1152/ajpregu.00223.2016

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