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Article

Interplay between tolerance mechanisms to copper and acid stress in Escherichia coli.

Proceedings of the National Academy of Sciences of the United States of America - 27 Jun 2017

Djoko Karrera Y, Phan Minh-Duy, Peters Kate M, Walker Mark J, Schembri Mark A, McEwan Alastair G

Abstract excerpt

Copper (Cu) is a key antibacterial component of the host innate immune system and almost all bacterial species possess systems that defend against the toxic effects of excess Cu. The Cu tolerance system in Gram-negative bacteria is composed minimally of a Cu sensor (CueR) and a Cu export pump (CopA). The cueR and copA genes are encoded on the chromosome typically as a divergent but contiguous operon. In...

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Identifiers

PMID: 28611214
DOI: 10.1073/pnas.1620232114
PMCID: PMC5495233

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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