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Article

LRP1-Dependent BMPER Signaling Regulates Lipopolysaccharide-Induced Vascular Inflammation.

Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 2017

Lockyer Pamela, Mao Hua, Fan Qiying, Li Luge, Yu-Lee Li-Yuan, Eissa N Tony, Patterson Cam, Xie Liang, Pi Xinchun

Abstract excerpt

OBJECTIVE: Bacterial endotoxin (lipopolysaccharide)-mediated sepsis involves dysregulated systemic inflammation, which injures the lung and other organs, often fatally. Vascular endothelial cells act as both targets and mediators of lipopolysaccharide-induced inflammatory responses. Dysfunction of endothelium results in increases of proinflammatory cytokine production and permeability leakage. BMPER (bone...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28596374
DOI: 10.1161/ATVBAHA.117.309521
PMCID: PMC5532067

Genes

BMPER
LRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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