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Article

Evaluation of methodology for the analysis of 'time-to-event' data in pharmacogenomic genome-wide association studies.

Pharmacogenomics - 1 Jun 2016

Syed Hamzah, Jorgensen Andrea L, Morris Andrew P

Abstract excerpt

AIM: To evaluate the power to detect associations between SNPs and time-to-event outcomes across a range of pharmacogenomic study designs while comparing alternative regression approaches. MATERIALS & METHODS: Simulations were conducted to compare Cox proportional hazards modeling accounting for censoring and logistic regression modeling of a dichotomized outcome at the end of the study. RESULTS: The Cox...

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Identifiers

PMID: 27248145
DOI: 10.2217/pgs.16.19
PMCID: PMC5542031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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