Article
Transcription Factor Networks derived from Breast Cancer Stem Cells control the immune response in the Basal subtype.
Scientific reports - 6 Jun 2017
da Silveira W A, Palma P V B, Sicchieri R D, Villacis R A R, Mandarano L R M, Oliveira T M G, Antonio H M R, Andrade J M, Muglia V F, Rogatto S R, Theillet C, du Manoir S, Tiezzi D G
Abstract excerpt
Breast cancer is the most common cancer in women worldwide and metastatic dissemination is the principal factor related to death by this disease. Breast cancer stem cells (bCSC) are thought to be responsible for metastasis and chemoresistance. In this study, based on whole transcriptome analysis from putative bCSC and reverse engineering of transcription control networks, we identified two networks associated...
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