Article
The β4 subunit of the voltage-gated calcium channel (Cacnb4) regulates the rate of cell proliferation in Chinese Hamster Ovary cells.
The international journal of biochemistry & cell biology - 1 Aug 2017
Rima Mohamad, Daghsni Marwa, De Waard Stephan, Gaborit Nathalie, Fajloun Ziad, Ronjat Michel, Mori Yasuo, Brusés Juan L, De Waard Michel
Abstract excerpt
The β subunits of Voltage-Gated Calcium Channel (VGCC) are cytosolic proteins that interact with the VGCC pore -forming subunit and participate in the trafficking of the channel to the cell membrane and in ion influx regulation. β subunits also exert functions independently of their binding to VGCC by translocation to the cell nucleus including the control of gene expression. Mutations of the neuronal Cacnb4 (β4)...
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