Article
Current modulation and membrane targeting of the calcium channel alpha1C subunit are independent functions of the beta subunit.
The Journal of physiology - 1 Jun 1999
Gerster U, Neuhuber B, Groschner K, Striessnig J, Flucher B E
Abstract excerpt
1. The beta subunits of voltage-sensitive calcium channels facilitate the incorporation of channels into the plasma membrane and modulate calcium currents. In order to determine whether these two effects of the beta subunit are interdependent or independent of each other we studied plasma membrane incorporation of the channel subunits with green fluorescent protein and immunofluorescence labelling, and current...
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