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Article

Requirement of voltage-gated calcium channel beta4 subunit for T lymphocyte functions.

Science (New York, N.Y.) - 7 Jan 2005

Badou Abdallah, Basavappa Srisaila, Desai Rooma, Peng You-Qing, Matza Didi, Mehal Wajahat Z, Kaczmarek Leonard K, Boulpaep Emile L, Flavell Richard A

Abstract excerpt

Calcium is known to play vital roles in diverse physiological processes, and it is known that voltage-gated calcium channels (Cav) mediate calcium influx in excitable cells. However, no consensus exists on the molecular identity of the calcium channels present in nonexcitable cells such as T lymphocytes. Here, we demonstrate that T lymphocytes express both regulatory beta4 and poreforming Cav1 alpha1 subunits of...

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Identifiers

PMID: 15637280
DOI: 10.1126/science.1100582

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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