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Article

Identification of 15 novel risk loci for coronary artery disease and genetic risk of recurrent events, atrial fibrillation and heart failure.

Scientific reports - 5 Jun 2017

Verweij Niek, Eppinga Ruben N, Hagemeijer Yanick, van der Harst Pim

Abstract excerpt

Coronary artery disease (CAD) is the major cause of morbidity and mortality in the world. Identification of novel genetic determinants may provide new opportunities for developing innovative strategies to predict, prevent and treat CAD. Therefore, we meta-analyzed independent genetic variants passing P <× 10-5 in CARDIoGRAMplusC4D with novel data made available by UK Biobank. Of the 161 genetic variants studied,...

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Source

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Identifiers

PMID: 28584231
DOI: 10.1038/s41598-017-03062-8
PMCID: PMC5459820

Genes

CAD
TGFB1
CDH13
ITGB5
RHOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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