Article
Molgenis-impute: imputation pipeline in a box.
BMC research notes - 19 Aug 2015
Kanterakis Alexandros, Deelen Patrick, van Dijk Freerk, Byelas Heorhiy, Dijkstra Martijn, Swertz Morris A
Abstract excerpt
BACKGROUND: Genotype imputation is an important procedure in current genomic analysis such as genome-wide association studies, meta-analyses and fine mapping. Although high quality tools are available that perform the steps of this process, considerable effort and expertise is required to set up and run a best practice imputation pipeline, particularly for larger genotype datasets, where imputation has to scale...
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