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Article

RNASET2, GPR174, and PTPN22 gene polymorphisms are related to the risk of liver damage associated with the hyperthyroidism in patients with Graves' disease.

Journal of clinical laboratory analysis - 1 Feb 2018

Zhang Qing, Liu Shaozheng, Guan Yanxing, Chen Qingjie, Zhang Qing, Min Xiang

Abstract excerpt

OBJECTIVES: This study was designed to unveil the association of GPR174 rs3827440, PTPN22 rs3789604, and RNASET2 rs9355610 with the onset of liver damage (LD) among the Graves' disease (GD) patients. METHODS: A total of 120 GD patients were divided into the none-LD and LD groups. Several indicators were detected for assessing liver functions, and genotypes of single nucleotide polymorphisms (SNPs) were...

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Topics

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Share to Genetic Predisposition to Disease
Share to Graves Disease
Share to Liver
Share to Polymorphism, Single Nucleotide
Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22
Share to Receptors, G-Protein-Coupled
Share to Ribonucleases
Share to Tumor Suppressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 28568286
DOI: 10.1002/jcla.22258
PMCID: PMC6817210

Genes

PTPN22
RNASET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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