Article
The Plasma Membrane Calcium ATPases and Their Role as Major New Players in Human Disease.
Physiological reviews - 1 Jul 2017
Stafford Nicholas, Wilson Claire, Oceandy Delvac, Neyses Ludwig, Cartwright Elizabeth J
Abstract excerpt
The Ca2+ extrusion function of the four mammalian isoforms of the plasma membrane calcium ATPases (PMCAs) is well established. There is also ever-increasing detail known of their roles in global and local Ca2+ homeostasis and intracellular Ca2+ signaling in a wide variety of cell types and tissues. It is becoming clear that the spatiotemporal patterns of expression of the PMCAs and the fact that their abundances...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.