Article
The plasma membrane calcium pumps: focus on the role in (neuro)pathology.
Biochemical and biophysical research communications - 19 Feb 2017
Brini Marisa, Carafoli Ernesto, Calì Tito
Abstract excerpt
The plasma membrane Ca2+ ATPase (PMCA pump) is a member of the superfamily of P-type pumps. It is organized in the plasma membrane with ten transmembrane helices and two main cytosolic loops, one of which contains the catalytic center. It also contains a long C-terminal tail that houses the binding site for calmodulin, the main regulator of the activity of the pump. The pump also contains a number of other...
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