Article
Calcium-ATPases: Gene disorders and dysregulation in cancer.
Biochimica et biophysica acta - 1 Jun 2016
Dang Donna, Rao Rajini
Abstract excerpt
Ca(2+)-ATPases belonging to the superfamily of P-type pumps play an important role in maintaining low, nanomolar cytoplasmic Ca(2+) levels at rest and priming organellar stores, including the endoplasmic reticulum, Golgi, and secretory vesicles with high levels of Ca(2+) for a wide range of signaling functions. In this review, we introduce the distinct subtypes of Ca(2+)-ATPases and their isoforms and splice...
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