Article
Polymorphisms of the CYP1A1 and CYP2E1 genes in head and neck squamous cell carcinoma risk.
Molecular biology reports - 1 Feb 2012
Cury Nathália Moreno, Russo Anelise, Galbiatti Ana Lívia Silva, Ruiz Mariângela Torreglosa, Raposo Luiz Sérgio, Maniglia José Victor, Pavarino Erika Cristina, Goloni-Bertollo Eny Maria
Abstract excerpt
Polymorphisms in genes that encode P450 cytochrome enzymes may increase carcinogen activation or decrease their inactivation and consequently, promote the development of cancer. The aims of this study were to identify the MspI-CYP1A1, PstI-CYP2E1 and DraI-CYP2E1 polymorphisms in patients with head and neck cancer and to compare with individuals without cancer; to evaluate the association of these polymorphisms...
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