Article
A genetic polymorphism in the CYP1B1 gene in patients with squamous cell carcinoma of the esophagus: an Iranian Mashhad cohort study recruited over 10 years.
Pharmacogenomics - 1 Apr 2018
Moghadam Azam Rastgar, Mehramiz Mehrane, Entezari Malihe, Aboutalebi Hamideh, Kohansal Fatemeh, Dadjoo Parisa, Fiuji Hamid, Nasiri Mohammadreza, Aledavood Seyed Amir, Anvari Kazem, Simab Saeideh Ahmadi, Khorrami Mohammad Sadegh, Moradi Ali, Hassanian Seyed Mahdi, Ferns Gordon A, Sales Soodabeh Shahid, Avan Amir
Abstract excerpt
AIM: Esophageal cancer is the eighth most common cancer globally and the seventh most common cause of cancer-related deaths in men. Recent studies have shown that CYP450, family 1, subfamily B, polypeptide 1, which plays a role in the metabolism of xenobiotics, is associated with several cancers. Therefore, in the present study we investigated the association between a genetic variant, CYP1B1-rs1056836 gene, with...
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