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Article

Two CHRN susceptibility variants for COPD are genetic determinants of emphysema and chest computed tomography manifestations in Chinese patients.

International journal of chronic obstructive pulmonary disease - 1 Jan 2017

Zhao Zhuxiang, Jiang Changbin, Zhao Dongxing, Li Yujun, Liang Chunxiao, Liu Weifeng, Wei Shuquan, Zhou Yumin, Zhao Ziwen, Ran Pixin

Abstract excerpt

Quantitative computed tomography (CT) measures of emphysema have been shown to be associated with increased mortality in humans, but genetic variants affecting the quantitative parameters of chest CT that measure degree of emphysema have not yet been examined. In this study, using available chest CT data from a total of 344 emphysema patients, we assessed the correlations between five chronic obstructive...

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Identifiers

PMID: 28553097
DOI: 10.2147/COPD.S134010
PMCID: PMC5439970

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