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Article

An efficient method to genotype the polymorphisms of cholinergic nicotinic receptor subunit genes and their associations with COPD onset risk.

Experimental lung research - 1 Jun 2016

Zhao Zhuxiang, Zhou Yumin, Li Yujun, Jiang Changbin, Zhao Dongxing, Zhao Ziwen, Liu Zhaohui, Ran Pixin

Abstract excerpt

BACKGROUND: Single-nucleotide polymorphisms (SNPs) in the cholinergic nicotinic receptor subunit genes on chromosome 15q25.1, including CHRNA3, CHRNB4 and CHRNA5, are well-established biomarkers of chronic obstructive pulmonary disease (COPD) and lung cancer. Thus, there is great demand for a rapid, easy and inexpensive method to detect these variations for purpose of risk prediction in large populations. AIM OF...

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Source

Identifiers

PMID: 27462996
DOI: 10.1080/01902148.2016.1197346

Genes

CHRNA3
CHRNA5
CHRNB4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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