Article
Interluekin-35 in Asthma and Its Potential as an Effective Therapeutic Agent.
Mediators of inflammation - 1 Jan 2017
Gao Peng, Su Zhenzhong, Lv Xuejiao, Zhang Jie
Abstract excerpt
Interleukin- (IL-) 35 is a member of the IL-12 cytokine family and a heterodimeric protein formed by Epstein-Barr-induced gene 3 (EBI3) and IL-12p35. Emerging evidence shows that IL-35 is a key player in the regulation of cellular communication, differentiation, and inflammation. Altered IL-35 expression has been found in disease conditions such as cancer, rheumatoid arthritis, and, more recently, asthma. In...
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