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Article

Interleukin-35 mediates mucosal immune responses that protect against T-cell-dependent colitis.

Gastroenterology - 1 Nov 2011

Wirtz Stefan, Billmeier Ulrike, Mchedlidze Tamuna, Blumberg Richard S, Neurath Markus F

Abstract excerpt

BACKGROUND & AIMS: The soluble hematopoietin receptor Epstein-Barr virus-induced protein (EBI)-3 is an immune regulator that has been associated with the pathogenesis of inflammatory bowel disease. However, the concept that EBI3 is part of an interleukin (IL)-27 heterodimer that mediates chronic inflammatory and autoimmune diseases has been challenged by the description of IL-35, a bioactive cytokine comprising...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intestinal Mucosa

Share to Minor Histocompatibility Antigens

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Source

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Identifiers

PMID: 21820391
DOI: 10.1053/j.gastro.2011.07.040
PMCID: PMC3624892

Genes

EBI3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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